Antibiotic resistance is a bacterial defense mechanism against antibiotics. It can rapidly spread from one bacterium to another. This makes antibiotics increasingly ineffective.
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The level of resistances against antibiotics is rising. This is a great challenge for physicians and scientists. Scientists within the DZIF research field “Healthcare-associated and Antibiotic-resistant bacterial Infections” aim to develop new strategies against the development and spread of resistance.
Viruses and bacteria do not stop at national borders. International collaboration is the only way to meet the global challenges in infection research. Since its foundation, the German Center for
With INCATE (INCubator for Antibacterial Therapies in Europe), the German Center for Infection Research (DZIF) has participated in the foundation of a European initiative to take up the fight against
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The DZIF working group "Antibacterial Vaccines and Diagnostics Development" (ACTIVATE) led by Alexander Klimka develops active and passive vaccines against bacterial pathogens and antibody-based rapid tests to detect antibiotic-resistant bacteria. In 2017, the World Health Organization (WHO) ...
Researchers at Karolinska Institutet, Umeå University, and DZIF scientists at the University of Bonn have identified a new group of molecules that have an antibacterial effect against many antibiotic
Ahead of the “World Antimicrobial Awareness Week” (November 18-24) 20 national and international organizations from academia, healthcare, global health and the pharmaceutical industry appealed today
The intestine of a healthy person contains hundreds of different bacteria that provide efficient protection against infections. However, if the equilibrium of this community, known as the microbiota
Enterobacteria such as Escherichia coli or Klebsiella pneumoniae are dreaded hospital germs that can cause serious intestinal and urinary tract infections. The risk of infection with these pathogens
Multidrug-resistant bacteria are spreading worldwide, and new antibiotics and strategies against deadly infectious diseases are urgently needed. With INCATE (INCubator for Antibacterial Therapies in
Increasingly insensitive to standard drugs: Multi-resistant pathogens are spreading worldwide and even in the near future could threaten the safe treatment of deadly infectious diseases. However, the