Antibiotic resistance is a bacterial defense mechanism against antibiotics. It can rapidly spread from one bacterium to another. This makes antibiotics increasingly ineffective.
Detailed description
The level of resistances against antibiotics is rising. This is a great challenge for physicians and scientists. Scientists within the DZIF research field “Healthcare-associated and Antibiotic-resistant bacterial Infections” aim to develop new strategies against the development and spread of resistance.
In the journal The Lancet, DZIF researchers from the Research Center Borstel and their colleagues from England and South Africa make the case for optimising tuberculosis drug development. They
For the population geneticist Ulrich Nübel almost everything revolves around gene sequences of bacterial strains. The scientist obtains a lot of information through analysing them: The course of
Dr Tanja Schneider has been researching the interactions of bacteria and antibiotics for over ten years. She knows almost all the antibiotic target sites and mechanisms of antibiotic action in detail
The first antibiotic against tuberculosis that has been developed in Germany is now ready for clinical testing. BTZ043, as the newly developed drug substance is called, is also effective against
The German Federal Ministry of Education and Research is joining forces with international partners in a new initiative to promote research into antimicrobial resistance (AMR). The aim is to fight
Early detection of antibiotic resistant pathogens can be life-saving. DZIF-scientists at the Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, have developed an
The global increase of tuberculosis patients is alarming, particularly the increase of cases of so-called multidrug-resistant tuberculosis (MDR-TB) in which the pathogen is insensitive to the most
Pseudomonas aeruginosa bacteria are hospital germs and are often resistant to common antibiotics. They can infect all human organs and implants, and can persist in the body for long periods of time in
Tsutsugamushi fever, or “scrub typhus”, is an infectious disease related to typhus, which is endemic in large parts of Asia. The disease has an estimated incidence of approximately one million cases
The National Reference Center at the Research Center Borstel has confirmed a Europe-wide outbreak of a multidrug-resistant Mycobacterium tuberculosis strain in 29 refugees from the Horn of Africa. The