Antimicrobial resistance | German Center for Infection Research

Short description

Antimicrobial resistance (AMR) occurs when bacteria, viruses, fungi or parasites no longer respond to antimicrobial drugs such as antibiotics, antivirals or antifungals. This occurs due to genetic changes in the microorganisms that enable them to evade the effect of the drugs. AMR is a major global health problem as it complicates the treatment of infections, leads to longer courses of disease and increases the risk of serious illness or death.

Oct 2020

Antimicrob Agents Chemother

Secretion of and self-resistance to the novel fibupeptide antimicrobial lugdunin by distinct ABC transporters in Staphylococcus lugdunensis

Autoren

Krauss S et al.

Jul 2020

Future Microbiol

Tackling antimicrobial resistance by exploring new mechanisms of antibiotic action

Autoren

Matos de Opitz CL

Sass P

University of Cologne

R-Net: Core network for the study of multidrug-resistant bacterial organisms

Implementation of evidence-based infection control practices to reduce healthcare-associated infection remains a national and international priority. R-Net investigates the effect of various interventions aimed at limiting the spread of infections due to multi-drug resistant organisms (MDRO) ...

Learning lessons from the coronavirus pandemic on containing other infections

Healthcare-associated infections have been growing continuously for years, resulting in hundreds of thousands of avoidable deaths each year. The main culprit is bacteria that have become resistant to

Global spread of the multi-resistant pathogen Stenotrophomonas maltophilia

An international consortium found a remarkable global spread of strains of a multi-resistant bacterium that can cause severe infections – Stenotrophomonas maltophilia. The study, published under the

University of Tübingen

BLOOMY-PREDICT – Bloodstream infections due to multidrug-resistant organisms

Bloodstream infections (BSI) are associated with high morbidity and mortality worldwide and are still considered as one of the most severe bacterial infections. The BLOOMY-PREDICT project is an observational study, which runs at five German university hospitals. Within the scope of the project ...

Feb 2020

EMBO Mol Med

Predicting antimicrobial resistance in Pseudomonas aeruginosa with machine learning-enabled molecular diagnostics

Autoren

Khaledi A et al.

Dec 2019

BMC Infect Dis

Antimicrobial resistance of bacteraemia in the emergency department of a German university hospital (2013-2018): potential carbapenem-sparing empiric treatment options in light of the new EUCAST recommendations

Autoren

Rothe K et al.

23 Jan 2020

Bernhard Nocht Institute for Tropical Medicine
Bernhard-Nocht-Strasse 74
20359 Hamburg
Germany

public

LCI symposium 2020 "Future strategies to overcome antimicrobial resistance"

Reconciling career and family life

Maria J.G.T. Vehreschild is a physician and scientist and represents the archetype “clinician-scientist” like few other. She has been Head of the Department of Infectious Diseases at Frankfurt