Enterobacteriaceae are a family of bacteria that includes many gram-negative rod-shaped bacteria.
Detailed description
Some members of the family enterobacteriaceae are typical gut bacteria, which only become harmful if they translocate into other regions of the body. Salmonella, Shigella and gut pathogenic Escherichia are also enterobacteriaceae. They do not belong to the normal gut flora but are always pathogenic.
Gram-negative bacteria are naturally insensitive to many antibiotics due to their additional outer membrane. In addition, the bacteria have acquired resistance to clinically used antibiotics in recent decades, resulting in multidrug-resistant bacteria. Novel classes of antibiotics are needed to ...
Colistin is a last-resort antibiotic that is usually only used for severe infections with resistant bacteria. This is due to its severe kidney-damaging side effects, which occur in around 30 percent
