A natural compound library is a collection of chemical substances, which can be used to screen for biological activities of choice.
Detailed description
Microorganisms and fungi produce substances that may have medically relevant effects. To better exploit this potential, respective substances are isolated and stored in natural compound libraries. They can then be analyzed with new molecular biological methods for interesting activities. The DZIF supports the development of active substances by setting up such a “Natural compound library”.
Every year on 24 March, we commemorate Robert Koch’s discovery of the tubercle bacillus. Almost 140 years later, tuberculosis is still the leading infectious disease with the most number of deaths
Professor Marc Stadler’s research group examines cultures of rare types of fungi and bacteria, predominantly from tropical regions, for their potential to develop new antibiotic substances. Thanks to international partnerships, these substances are isolated, identified and subsequently transferred ...
Breaking down bacterial biofilms in order to lure the pathogens out of hiding is one of chemist Dr Alexander Titz’s goals. The junior research group leader from the Helmholtz Institute for
From chemistry to biology to medicine—during the course of his career, Mark Brönstrup repeatedly crossed the boundaries between these disciplines. So it comes as no surprise that today he is head of
For the population geneticist Ulrich Nübel almost everything revolves around gene sequences of bacterial strains. The scientist obtains a lot of information through analysing them: The course of
One of them speaks of “treasures, waiting to be found” while the other focuses on new “compounds”, but both Timo Niedermeyer and Leonard Kaysser mean the same thing and have a mutual goal: As
Dr Tanja Schneider has been researching the interactions of bacteria and antibiotics for over ten years. She knows almost all the antibiotic target sites and mechanisms of antibiotic action in detail
The natural substance researcher Prof Rolf Müller has been awarded the 2016 PHOENIX Pharmaceutical Science Award worth 10,000 euro. Müller heads the Helmholtz Institute for Pharmaceutical Research
