Biofilm | German Center for Infection Research

Short description

A biofilm is a layer of mucus that is produced by microorganisms, which are embedded in this layer themselves. Biofilm-producing bacteria pose a medical problem.

Detailed description

The slimy layer consisting of sugar and proteins protects the embedded bacteria against the and increases their insensibility against antibiotics. Bacteria on surfaces like teeth or medical implants organize themselves into communities, which are able to communicate with each other. Medically relevant biofilm-producing pathogens are , pseudomonads and streptococci.

Mar 2024

Fitoterapia

Discovery of novel secondary metabolites from the basidiomycete Lentinus cf. sajor-caju and their inhibitory effects on Staphylococcus aureus biofilms

Autoren

Zeng H et al.

Jul 2023

J Fungi

Inhibitory Effects of the Fungal Pigment Rubiginosin C on Hyphal and Biofilm Formation in Candida albicans and Candida auris

Autoren

Zeng H et al.

Jun 2023

Cell

Biofilm formation on human immune cells is a multicellular predation strategy of Vibrio cholerae

Autoren

Vidakovic L et al.

Apr 2023

Org Biomol Chem

Design of non-cytotoxic 6,7-dihydroxycoumarin-5-carboxylates with antibiofilm activity against Staphylococcus aureus and Candida albicans

Autoren

Zscherp R et al.

Feb 2023

Int J Mol Sci

Identification of Compounds Preventing A. fumigatus Biofilm Formation by Inhibition of the Galactosaminogalactan Deacetylase Agd3

Autoren

Seegers CII et al.

Fluorescence micrograph of blue-stained cells on a black background. In the left half of the image, green-stained Lec A-proteins bind to the cells. In the right half of the image, only blue-stained cells are visible.

Sugar-based inhibitors disarm the pathogen Pseudomonas aeruginosa

The hospital germ Pseudomonas aeruginosa forms biofilms, a kind of mucus layer, to protect itself from attack by the immune system or antibiotics. To form this sticky layer, as well as to successfully

Jul 2017

Sci Rep