Staphylococci | German Center for Infection Research

Short description

Staphylococci are bacteria that can cause disease in humans. One example is the dreaded hospital Staphylococcus aureus.

Detailed description

Some staphylococci are part of the natural human microflora. Others are pathogens, which cause infections under specific circumstances like for example immune deficiencies.

Prof Achim Hoerauf in his laboratory at the University Hospital Bonn

New antibiotic against river blindness and lymphatic filariasis pathogens

A team led by Prof Achim Hoerauf in the German Center for Infection Research (DZIF) is further developing the antibiotic corallopyronin A as a treatment for the neglected tropical diseases river

Prof Ulrich Kubitscheck, Jan-Samuel Puls, Dominik Brajtenbach and Dr Fabian Grein (from left to right), all in white lab coats, photographed as a group in the lab.

Lantibiotics: antibacterial substance with new mechanism of action discovered

Many bacteria produce substances to gain an advantage over competitors in their highly competitive natural environment. Researchers at the University Hospital Bonn (UKB), the University of Bonn and

Jul 2023

Liver Int

Rifaximin may induce rifampicin resistance in coagulase-negative staphylococci

Autoren

Schulte LM et al.

Aug 2023

Probiotics Antimicrob Proteins

Genomic Analysis of Bacteriocin-Producing Staphylococci: High Prevalence of Lanthipeptides and the Micrococcin P1 Biosynthetic Gene Clusters

Autoren

Fernández-Fernández R et al.

Oct 2014

Angew Chem Int Ed Engl

Disciformycins A and B: 12-membered macrolide glycoside antibiotics from the myxobacterium Pyxidicoccus fallax active against multiresistant staphylococci

Autoren

Surup F et al.

New group of antibacterial molecules identified

Researchers at Karolinska Institutet, Umeå University, and DZIF scientists at the University of Bonn have identified a new group of molecules that have an antibacterial effect against many antibiotic

Tübingen research team develops new strategy against sepsis

Some cases of bloodstream infections are mild, but many have a fatal outcome – the reasons for these differences have remained in the dark despite decades of research. Researchers from the University

From harmless skin bacteria to dreaded pathogens

An international research team, led by scientists from Tübingen and the German Center for Infection Research (DZIF) discovers additional component in staphylococcal cell wall that turns the bacterium

Novel Antibiotics: The DZIF brings two German projects into the CARB-X funding

The organization CARB-X globally supports projects, which develop new drugs against antibiotic-resistant pathogens. Since the beginning of 2019 the DZIF is one of seven members in the CARB-X

University of Bonn

Corallopyronin - A development through to phase I trial

More than 21 million people in Africa are infected with the threadworm Onchocerca volvulus, the pathogen causing river blindness. About one in ten of those affected goes blind. What is needed are active agents that kill the long-lived adult worms. With Corallopyronin A, DZIF scientists have found an ...