CD4 T lymphocytes form a subgroup of T lymphocytes that is responsible for cell-mediated immune responses.
Synonyms
T helper cell
CD4 cells
Detailed description
T lymphocytes carrying the surface antigen CD4 are called T helper cells. After activation, they release substances that are either involved in cell-mediated immunity or that stimulate B cell immune responses. HIV infects mainly this T lymphocyte subgroup.
Colistin is a last-line reserve antibiotic for the treatment of infections caused by extremely multidrug-resistant (XDR) Gram-negative bacteria. The recent emergence and global spread of the mobile
Scanning electron micrograph: C. difficile cells were provided by Nicole Metzendorf from the Department of Microbial Physiology and Molecular Biology, Institute of Microbiology, and imaged by Rabea Schlüter, Imaging Center of the Department of Biology, University of Greifswald, Germany.
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Infections with the bacterium Clostridioides difficile (C. difficile for short) frequently recur due to permanent stages remaining in the intestine. A drug that also effectively combats the permanent
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Dr. Victoria Ingham from Heidelberg University Hospital and the German Center for Infection Research (DZIF) is investigating the potential dual effect of a new insecticide for mosquito nets. The
Potentially life-threatening infectious diseases (such as HIV/AIDS at the time) were among the first indications for gene therapy as early as the 1990s. Today, cell and gene therapy strategies are
We still do not understand exactly how antibiotics kill bacteria. However, this understanding is necessary if we want to develop new antibiotics. And that is precisely what is urgently needed, because
This is what ideal medicine would look like: Doctors could specifically alter molecular processes in diseased cells in the body and thus causally cure patients. This is the goal of the German Centers
The human immunodeficiency virus HIV-1 is able to infect various tissues in humans. Once inside the cells, the virus integrates its genome into the cellular genome and establishes persistent
