Resistance gene | German Center for Infection Research

Short description

A resistance gene contains the information for the production of a protein that makes an antibiotic ineffective and hence confers resistance against an antibiotic to a .

Detailed description

Resistance genes are usually found on a ring-shaped piece of DNA, the plasmid. Like this, they can easily be passed on from one bacterium to another. Plants can possess resistance genes as well. They are usually directed against herbicides and pests.

Tailor-made therapy of multi-resistant tuberculosis

The successful treatment of multidrug-resistant tuberculosis requires clarification in advance as to which antibiotics the pathogens are resistant to. Classic testing in the laboratory is very time

Oct 2020

Antibiotics (Basel)

Antibiotic Resistance and Mobile Genetic Elements in Extensively Drug-Resistant Klebsiella pneumoniae Sequence Type 147 Recovered from Germany

Autoren

Xanthopoulou K et al.

University of Cologne

R-Net: Core network for the study of multidrug-resistant bacterial organisms

Implementation of evidence-based infection control practices to reduce healthcare-associated infection remains a national and international priority. R-Net investigates the effect of various interventions aimed at limiting the spread of infections due to multi-drug resistant organisms (MDRO) ...

Siblings can also differ from one another in bacteria

A research team from the University of Tübingen and the German Center for Infection Research (DZIF) is investigating how pathogens influence the immune response of their host with genetic variation

Mar 2020

Genome Med

Phylogenetically informative mutations in genes implicated in antibiotic resistance in Mycobacterium tuberculosis complex

Autoren

Merker M et al.

Global spread of the multi-resistant pathogen Stenotrophomonas maltophilia

An international consortium found a remarkable global spread of strains of a multi-resistant bacterium that can cause severe infections – Stenotrophomonas maltophilia. The study, published under the

Jun 2019

Antimicrob Agents Chemother

Isoniazid Resistance in Mycobacterium tuberculosis Is a Heterogeneous Phenotype Composed of Overlapping MIC Distributions with Different Underlying Resistance Mechanisms

Autoren

Ghodousi A et al.

Jun 2019

J Med Microbiol

Generation and selection of antibodies for a novel immunochromatographic lateral flow test to rapidly identify OXA-23-like-mediated carbapenem resistance in Acinetobacter baumannii

Autoren

Mertins S et al.

Sep 2019

Front Cell Infect Microbiol

Genetic Features of Antarctic Acinetobacter radioresistens Strain A154 Harboring Multiple Antibiotic-Resistance Genes

Autoren

Opazo-Capurro A et al.

Mar 2016

Lancet Infect Dis

Colistin resistance gene mcr-1 in extended-spectrum β-lactamase-producing and carbapenemase-producing Gram-negative bacteria in Germany

Autoren

Falgenhauer L et al.