Zika virus | German Center for Infection Research

Short description

The Zika virus is a flavivirus that is transmitted by the mosquito Aedes aegypti and causes fever, rashes, joint pains and eye inflammation in humans.

Detailed description

Zika virus infections have been observed in many tropical and subtropical countries. The transmitting Aedes aegypti mosquito is not found in Germany. During a major epidemic in South America in 2015-2017, a link was found between infection in pregnant women and brain malformations in newborns.

Horizon Europe project DEFENDER: New targets for antiviral therapies

The interdisciplinary project DEFENDER is developing innovative approaches to combat (re-)emerging viruses. The project, coordinated by the Leibniz Institute of Virology (LIV), is being funded with

Dec 2023

Nat Commun

Zika virus remodelled ER membranes contain proviral factors involved in redox and methylation pathways

Autoren

Denolly S et al.

Nov 2023

Nat Commun

Zika virus prM protein contains cholesterol binding motifs required for virus entry and assembly

Autoren

Goellner S et al.

Jul 2023

PLoS Negl Trop Dis

The Aedes aegypti RNA interference response against Zika virus in the context of co-infection with dengue and chikungunya viruses

Autoren

Leggewie M et al.

Der Preisträger Ralf Bartenschlager steht in der Mitte des Bildes, rechts neben ihm steht Nadja Käding von der DZIF Academy, links neben Prof. Bartenschlager steht DZIF-Vorstandsvorsitzender Prof. Dirk Busch.

Virologist Ralf Bartenschlager honoured with the DZIF Prize for Translational Infection Research

The German Center for Infection Research (DZIF) honours the virologist Prof. Dr Dr h. c. Ralf Bartenschlager from the Heidelberg University Hospital. The DZIF Prize for Translational Infection

Feb 2023

EMBO J

Extracellular vesicles from Zika virus-infected cells display viral E protein that binds ZIKV-neutralizing antibodies to prevent infection enhancement

Autoren

Zhao F et al.

Shown on a black background are about 12 nuclei of lung cells in purple and a green-stained oval SARS-CoV-2 virus particle.

Bacterial weapons against viral diseases

The COVID-19 pandemic has dramatically demonstrated that the development of effective agents against viral pathogens is of great importance for global health. Although effective vaccines are available

Nov 2017

PLoS Negl Trop Dis

Zika virus displacement by a chikungunya outbreak in Recife, Brazil

Autoren

Magalhaes T et al.

Mar 2017

Cell Rep

Ultrastructural Characterization of Zika Virus Replication Factories

Autoren

Cortese M et al.

Nov 2017

Emerg Microbes Infect

Specific detection of dengue and Zika virus antibodies using envelope proteins with mutations in the conserved fusion loop

Autoren

Rockstroh A et al.