The genus Acinetobacter comprises extremely resistant gram-negative bacteria, which have developed resistance against almost all available antibiotics.
Actinomycetes are gram-positive bacteria, which are commonly found in nature. They produce interesting natural products, which are the basis of many of the antibiotics developed so far.
An animal model is a non-human animal species used in biomedical research because it can mimic aspects of a biological process or disease that occur in humans.
Antibiotic resistance is a bacterial defense mechanism against antibiotics. It can rapidly spread from one bacterium to another. This makes antibiotics increasingly ineffective.