A resistance gene contains the information for the production of a protein that makes an antibiotic ineffective and hence confers resistance against an antibiotic to a pathogen.
Detailed description
Resistance genes are usually found on a ring-shaped piece of DNA, the plasmid. Like this, they can easily be passed on from one bacterium to another. Plants can possess resistance genes as well. They are usually directed against herbicides and pests.
The microbiome, i.e. the microorganisms that colonise our gut and help with digestion, weighs around one and a half kilograms. It consists primarily of bacteria and also has a protective effect
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Most antibiotics used in human medicine originate from natural products derived from bacteria and other microbes. Novel microorganisms are therefore a promising source of new active compounds—also for
Antimicrobial resistance (AMR) is one of the top global public health and development threats. According to the World Health Organisation (WHO), an estimated 4.95 million deaths were associated with
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Many bacteria produce substances to gain an advantage over competitors in their highly competitive natural environment. Researchers at the University Hospital Bonn (UKB), the University of Bonn and
While tuberculosis (TB) has become relatively rare in Germany and other industrialised nations, around ten million people contract the bacterial infection every year, especially in resource-poorer
A recent clinical study shows that ganfeborole could be a promising candidate for the safe and effective treatment of pulmonary tuberculosis. Using microbiological testing and innovative imaging
BioVersys AG, a multi-asset, clinical stage biopharmaceutical company focusing on research and development of novel antibacterial products for serious life-threatening infections caused by multi-drug
INCATE (the INCubator for Antibacterial Therapies in Europe) and Kineticos AMR Accelerator Fund I (KAMRA I), have announced the beginning of a new collaboration that aims to enhance the support for
