In research, translation refers to the implementation of findings from basic research in the clinic or in therapeutic applications.
Detailed description
Ideally, feasibility should already be considered in the design of basic research. Only translation makes results of basic research practically accessible for people. The slogan “From bench to bedside” describes the aim of translational research.
Developing a new medication usually takes more than ten years. Out of the several thousand substances investigated in basic and pre-clinical research, only one or two candidates are approved by
What is translation? Basic scientific and medical research are the foundation for gaining knowledge and driving progress. The scientists at the DZIF pursue the aim of strategically transferring the
The DZIF was founded with the aim of conducting translational infection research. Research results should reach patients more quickly from the laboratory. In order to achieve this goal, doctors and
A sequencing platform will be made available as part of this research unit, whose focus is translational microbiome research. The know-how for sequencing and bioinformatic data analysis is used in various preclinical and clinical trials at the DZIF. One example is the so-called SPEKTRUM study, which ...
The intestinal microbiome plays a crucial role in the course of infections. As part of this research platform, Prof. Bärbel Stecher and her team are examining what exactly happens when gram-negative pathogens and opportunists colonise the intestine. An important project is targeting ...
This research group, led by Professor Marylyn Addo, initiates and coordinates translational research in the field of emerging infections with a particular focus on Ebola, MERS, Lassa and Crimean-Congo haemorrhagic fever. Immunology studies, vaccine development, testing of novel anti-infectives and ...
In addition to analyzing the replication mechanisms of the hepatitis B (HBV) and D (HDV) viruses, the work of Prof. Stephan Urban and his team focuses on the development of new active substances and drugs against these pathogens. With Bulevirtide (formerly Myrcludex B), which blocks the binding and ...
Professor Markus Cornberg is Clinical Director of the Helmholtz Centre for Infection Research (HZI) and Co-Director of the Centre for Individualised Infection Medicine (CiiM). He and his translational research group provide the necessary link between hospitals, the HZI, the HepNet Study-House trial ...
According to the World Health Organisation (WHO), the global emergence of antibiotic resistance is one of the greatest threats to human health. In light of this, it is of utmost importance that new agents and target sites for drugs are identified. Once new lead compounds have been identified, the ...
The HepNet Study-House connects individual study centers in the field of hepatitis research and creates a central platform to conduct clinical studies (Investigator Initiated Trials) and build patient cohorts in the field of viral hepatitis. On the one hand, the Study-House is a contact point for ...
