Multidrug resistance means that bacteria or viruses are insensitive towards various antibiotics or antivirals, respectively.
Synonyms
Multiple drug resistance
Detailed description
There is a general increase of resistances against antibiotics. Infections with multidrug-resistant pathogens pose a serious problem as their treatment with antibiotics is difficult or not possible any more.
Bloodstream infections (BSI) are associated with high morbidity and mortality worldwide and are still considered as one of the most severe bacterial infections. The BLOOMY-PREDICT project is an observational study, which runs at five German university hospitals. Within the scope of the project ...
Maria J.G.T. Vehreschild is a physician and scientist and represents the archetype “clinician-scientist” like few other. She has been Head of the Department of Infectious Diseases at Frankfurt
A research team from the Universities of Tübingen and Göttingen as well as from the German Center for Infection Research has investigated the mode of action of a new class of antibiotics that is
Every year on 24 March, we commemorate Robert Koch’s discovery of the tubercle bacillus. Almost 140 years later, tuberculosis is still the leading infectious disease with the most number of deaths
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Tuberculosis treatment still entails the intake several antibiotics over a period of many months and is torturous for many patients. The pathogen’s increasing multidrug resistance additionally
The challenge of antibiotic drug development today is the discovery and optimisation of novel bioactive compounds that do not show cross-resistances with clinically applied antibiotics, ideally due to a novel mode of action (MoA) which adresses unexploited microbial targets. In the case of ...
Christoph Lange was recently appointed as Medical Director of the Research Center Borstel. From here, he substantially contributes to clinical tuberculosis research in Europe, also monitoring the