Multidrug resistance means that bacteria or viruses are insensitive towards various antibiotics or antivirals, respectively.
Synonyms
Multiple drug resistance
Detailed description
There is a general increase of resistances against antibiotics. Infections with multidrug-resistant pathogens pose a serious problem as their treatment with antibiotics is difficult or not possible any more.
The German Research Foundation (DFG) and the French Agence National de la Recherche (ANR) are now funding the project "Characterization of novel natural product binding sites in the DNA gyrase of
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Pathogenic strains of Salmonella inject effector proteins into the cells of the gastrointestinal tract to invade and multiply within them. The bacteria are usually ingested with contaminated food
Gram-negative bacteria are naturally insensitive to many antibiotics due to their additional outer membrane. In addition, the bacteria have acquired resistance to clinically used antibiotics in recent decades, resulting in multidrug-resistant bacteria. Novel classes of antibiotics are needed to ...
Antimicrobial resistance (AMR) is one of the most urgent challenges facing global health and development. Described as a “creeping pandemic” by the G7 forum of leading economic nations, AMR occurs
The novel active agent HY-133, which was developed by HYpharm and prepared for clinical trials in collaboration with the German Center for Infection Research (DZIF) and universities in Tübingen
UNITE4TB—an international public-private partnership aiming to accelerate the development of innovative tuberculosis treatments—has announced the successful completion of participant recruitment for
Proteins form different conformations in combination with other proteins—as multimers or heterocomplexes—than when they are present as monomers. Static descriptions of protein structures are therefore often not sufficient to describe their dynamic properties. Nevertheless, current simulations of ...
Antibiotic resistance is one of the challenges facing mankind in the 21st century. This includes antibiotic-resistant tuberculosis. Just in time for World Tuberculosis Day on 24 March 2024, the
