Working Groups

Prof. Ernst's working group operates at the interface of molecular microbiology, genomics, epidemiology and chemical biology to identify, investigate, and target unrecognised pathways in persistent and multidrug-resistant infections. To this end, the group conducts mechanistic investigations ...

A sequencing platform will be made available as part of this research unit, whose focus is translational microbiome research. The know-how for sequencing and bioinformatic data analysis is used in various preclinical and clinical trials at the DZIF. One example is the so-called SPEKTRUM study, which ...

Humanised mice carrying human genes or cells, for example, are a crucial model for disease research and drug development. Generating them and keeping them in optimal conditions requires a lot of know-how and experience. Therefore, a professional central unit with humanised mice (Humanized Mouse Core ...

Andreas Moosmann’s research group investigates the immune system’s responses to viruses, particularly T cell responses. Widespread viruses such as the Epstein-Barr virus and the cytomegalovirus are at the core of their interest. After infecting healthy individuals, these viruses often remain in the ...

A detailed understanding of cellular immune responses in acute and chronic hepatitis is essential for the development of new drugs against hepatitis B and D infections. This means that standardised immunomonitoring under the necessary security conditions of risk level 3 is required, where immune ...

Professor Andreas Pichlmair and his team study the interactions between viruses and the human immune system. They aim to determine how the immune system reacts to an external attack and how this affects the pathogen. Human cells have developed a technique to combat viruses. However, viruses ...

Professor Markus Cornberg and his translational research group provide the necessary link between hospitals, the HepNet Study House trial platform and scientific activities at the DZIF. At the Hannover Medical School, Cornberg is clinically responsible for the Hepatitis Outpatient Clinic and for the ...

New HIV infections occur mostly outside of Europe. That is why the DZIF has set up its own task force to coordinate clinical trials on location (mainly in Africa). The "International Clinical Trials Unit" gives DZIF member institutions access to large existing cohorts and biobanks that they can use ...

The use of insecticides has been very successful in controlling the transmission of malaria pathogens over the past decades. However, this success is threatened by the widespread and intense levels of insecticide resistance in Anopheles mosquitoes, which transmit malaria. The working group of ...

The research group “Mathematical models and biostatistics” supports scientists in the field of malaria research with bioinformatics methods. Their aim is to more accurately determine the courses of infection, the spread of pathogens and human immune responses. In addition, their studies provide data ...