Antibiotic resistance is a bacterial defense mechanism against antibiotics. It can rapidly spread from one bacterium to another. This makes antibiotics increasingly ineffective.
Detailed description
The level of resistances against antibiotics is rising. This is a great challenge for physicians and scientists. Scientists within the DZIF research field “Healthcare-associated and Antibiotic-resistant bacterial Infections” aim to develop new strategies against the development and spread of resistance.
Antimicrobial resistance (AMR) is one of the greatest challenges for global health and development. According to estimates by the World Health Organisation (WHO), almost five million deaths worldwide
Microorganisms produce a wide variety of natural products that can be used as active agents to treat diseases such as infections or cancer. The blueprints for these molecules can be found in the
Two DZIF junior scientists—Prof Philipp Schommers and Dr Alexander Simonis—have been honoured with silver medals by the Walter Siegenthaler Society for their fundamental medical research in the field
Gram-negative bacteria are naturally insensitive to many antibiotics due to their additional outer membrane. In addition, the bacteria have acquired resistance to clinically used antibiotics in recent decades, resulting in multidrug-resistant bacteria. Novel classes of antibiotics are needed to ...
Prof. Tanja Schneider, Head of the Institute of Pharmaceutical Microbiology at the University Hospital Bonn (UKB) and Deputy Coordinator of the “New Antibiotics” research area at the German Center for
Antibacterial drugs are important for treating infections. However, increasing bacterial resistance to current drugs—making them ineffective or only partially effective—means that new drugs are
Antimicrobial resistance (AMR) is one of the most urgent challenges facing global health and development. Described as a “creeping pandemic” by the G7 forum of leading economic nations, AMR occurs
Professors Ivo Boneca (Institut Pasteur, Paris), Mark Brönstrup (Helmholtz Centre for Infection Research, Braunschweig, and German Center for Infection Research), and Christophe Zimmer (University of
According to the WHO, antimicrobial resistance (AMR) is one of the ten greatest threats to global health. In the EU alone, around 35,000 people die every year from antibiotic-resistant infections. The
The project deals with the epidemiology of Campylobacter jejuni and Campylobacter coli, the most common acute foodborne diarrhoeal pathogens in humans worldwide. In addition to acute diarrhoeal diseases, these bacteria may also be involved in chronic inflammatory bowel diseases in humans. Antibiotic ...
