Clinical phase | German Center for Infection Research

Short description

The clinical phase is a phase in drug development, in which the substance is tested in humans.

Detailed description

It follows the preclinical phase, in which, for example, toxicity of the potential drug is investigated. The clinical part is divided into three phases, which look at different aspects. At the beginning, tolerance is tested in healthy people in a “First-in-human” study. Next, the effect in patients is investigated and, finally, effectiveness and harmlessness need to be confirmed.

First drug for hepatitis D has been approved by European Commission

Joint press release from Heidelberg University and the German Center for Infection Research (DZIF)

What started off as basic research 25 years ago has now led to a successfully approved drug: The

Apr 2019

J Hepatol

GS-13-Final results of a multicenter, open-label phase 2 clinical trial (MYR203) to assess safety and efficacy of myrcludex B in cwith PEG-interferon Alpha 2a in patients with chronic HBV/HDV co-infection

Autoren

Wedemeyer H et al.

A vaccine candidate against The Epstein-Barr virus

At the DZIF, EBV research has been ongoing for years. Now a promising candidate is passing from the laboratory to quality assured production. Subsequently, preclinical and early clinical

Development of a MERS vaccination

The production of a against the harmful is funded by the international vaccine initiative CEPI (Coalition for Epidemic Preparedness Innovations) with up to 36 million dollars

New active agent against hospital pathogens

Scientists from the universities of Greifswald, Tübingen and Munich are working with the company HYpharm GmbH to develop a drug to combat the dreaded hospital . The

Clinical trials for SARS-CoV-2 vaccine set to start September

Joint vaccine development under the roof of the DZIF: Vaccine is currently being manufactured for use in clinical trials

A potential vaccine against SARS-CoV-2 is to undergo first clinical trials on

Promising MERS coronavirus vaccine trial on humans—useful insights for vaccine development against SARS-CoV-2

Over the past 20 years, coronaviruses have been responsible for large outbreaks, resulting in severe respiratory illness and a number of deaths. These include the SARS coronavirus outbreak in 2002

German Centers for Health Research

Successful translational research at the DZG The main aim of the German Federal Government's health research programme is to be able to combat major widespread diseases more effectively. The Federal

Tuberculosis: New drug substance BTZ-043 is being tested on patients for the first time

The Tropical Institute at the Hospital of the Ludwig-Maximilians-University (LMU) Munich is currently conducting a clinical study led by Professor Michael Hoelscher. Since mid-November, the first

Reconciling career and family life

Maria J.G.T. Vehreschild is a physician and scientist and represents the archetype “clinician-scientist” like few other. She has been Head of the Department of Infectious Diseases at Frankfurt